February 27, 2025

Louisville vs. Ole Miss – Prediction, Preview Monday Sept 6th

2 min read

It’s a Labor Day Showdown between The Cardinals and The Rebels at Mercedes-Benz Stadium, in Atlanta, Georgia.


The Rebels will take to the field on Monday night without their second-year coach Lane Kiffin who tested positive for COVID-19 on Saturday.


Ole Miss returns nine starters from a defense that was non existant last year to say the least.


The Rebels’ SEC-worst defense was plagued primarily by an inadequate pass rush (16 sacks).
In 2021 the Rebela roster transformed, with the additions of 12 freshmen and junior college transfers as well as senior safety Jake Springer, senior linebacker Chance Campbell and junior cornerback Deantre Prince.

Reputable online sports book America’s Bookie has the following numbers posted for this game.

When: Monday September 6, 2021

Game Time: 8:00 PM ET

Where: Mercedes-Benz Stadium, Atlanta, Georgia

TV Network: ESPN2

Louisville vs. Ole Miss spread: Ole Miss -10

Louisville vs. Ole Miss over-under: 76 points

This will be the first-ever meeting between these two schools. Ole Miss is coming off a 5-5 season in coach Kiffin’s first season as head coach in 2020. Louisville is coming off of very a disappointing 4-7 campaign that was filled inconsistancy it made it hard to watch these kids for a full game.

Since this is the first meeting between these teams,trends on head to head play will simply not exist.

The Cardinals return seven starters from a defense that was fourth in the ACC in yards allowed last season, a jump of eight spots from 2019.

We believe the hype on this game doesnt marit The Rebels as a (-10) chalk. The Rebels defense struggled at times last season and Louisville has some weapons on offense and should be able to keep the Rebels close on the scoreboard.

Team Trends:

The total has gone OVER in 12 of Louisville’s last 16 games.
Louisville are 3-7 SU in their last 10 games.
The total has gone OVER in 4 of Louisville’s last 5 games against an opponent in the Southeastern conference.
Louisville are 3-6 SU in their last 9 games played in September.
Louisville are 6-2 ATS in their last 8 games played in week 1.
Louisville are 4-1 ATS in their last 5 games played on a Monday.
Louisville are 1-6 SU in their last 7 games when playing as the underdog.
Mississippi are 4-1 SU in their last 5 games.
The total has gone OVER in 5 of Mississippi’s last 6 games played in September.
The total has gone OVER in 4 of Mississippi’s last 5 games played in week 1.
Mississippi are 13-4 SU in their last 17 games when playing as the favourite.

Mississippi are 4-1 SU in their last 5 games.
The total has gone OVER in 5 of Mississippi’s last 6 games played in September.
The total has gone OVER in 4 of Mississippi’s last 5 games played in week 1.
Mississippi are 13-4 SU in their last 17 games when playing as the favourite

Take the Cardinals with the points in their season-opener against Ole Miss Prediction: Louisville Cardinals +10

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